Attendees are encouraged to register in advance for vendor lunch seminars on Monday and Tuesday. See listings and registration links below.
MONDAY, March 4, 2019 | 12:15 - 01:30 pm, Regency Room
RSVP for Bruker Lunch Seminar
During this informative seminar, the technology behind the timsTOF Pro, a novel QTOF instrument with a Trapped Ion Mobility Spectrometry (TIMS) front end enabling accurate CCS determination, and with 100+ Hz MSMS sequencing speeds via Parallel Accumulation Serial Fragmentation (PASEF) will be described.
12:20 - 12:35 pm - timsTOF Pro and PASEF, 120 Hz MSMS and CCS Determination Decipher Phosphopeptide Positional isomers; Christopher Adams, Bruker Daltonics, West Coast Proteomics Manager
12:35 - 1:20 pm - Unlocking the Power of the Fourth Dimension: MaxQuant for TimsTOF Pro; Juergen Cox, Research group leader at the Max Planck Institute of Biochemistry, Martinsried, Germany
TUESDAY, March 5, 2019 | 12:15 - 1:30 pm, Potomac Room
RSVP URL will be posted here soon!
Fast-Track your Quantitative Proteomics with Microflow SWATH® Acquisition; Christie Hunter, SCIEX
Proteomics has typically been done using nanoflow LC for sensitivity but with slow time to results. Increasingly, labs are using microflow LC for some applications when sufficient sample is available, to accelerate throughput. The ability to utilize both nanoflow and microflow rates enables maximum functionality. Therefore easy switching between flow regimes is important for full workflow flexibility. The new OptiFlow™ Source and Interface with the NanoLC™ 400 system allows for easy switching in minutes between flow regimes on the TripleTOF® 6600 system. One key quantitative workflow that has proven to work extremely well with microflow is SWATH® Acquisition. An extensive evaluation of impact on the gradient length vs proteins quantified has been performed using gradients as short as 5 minutes and results will be reported. Impact on quantitative measurements will be presented as well as results from biological studies.
TUESDAY, March 5, 2019 | 12:15 - 1:30 pm, Regency Room
Join us for our seminar. Lunch will be served. RSVP not required.
A Multi-omic Targeted Assay for Detecting Alterations in Signaling
Emily Chen, Ph.D., Thermo Fisher Scientific
Multiplex IP Assays Combined with Targeted Mass Spectrometry Reveals Signaling Pathway Changes in Lung Tumor Patient-derived Xenograft Models
Jonathan Krieger, Ph.D.,SPARC Biocentre at the Hospital for Sick Children